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CLAffinity: A Software Tool for Identification of Optimum Ligand Affinity for Competition-Based Primary Screens
[Image: see text] A simplistic assumption in setting up a competition assay is that a low affinity labeled ligand can be more easily displaced from a target protein than a high affinity ligand, which in turn produces a more sensitive assay. An often-cited paper correctly rallies against this assumpt...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131445/ https://www.ncbi.nlm.nih.gov/pubmed/35442032 http://dx.doi.org/10.1021/acs.jcim.2c00285 |