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Enzymatic N-Allylation of Primary and Secondary Amines Using Renewable Cinnamic Acids Enabled by Bacterial Reductive Aminases

[Image: see text] Allylic amines are a versatile class of synthetic precursors of many valuable nitrogen-containing organic compounds, including pharmaceuticals. Enzymatic allylic amination methods provide a sustainable route to these compounds but are often restricted to allylic primary amines. We...

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Detalles Bibliográficos
Autores principales: Aleku, Godwin A., Titchiner, Gabriel R., Roberts, George W., Derrington, Sasha R., Marshall, James R., Hollfelder, Florian, Turner, Nicholas J., Leys, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131517/
https://www.ncbi.nlm.nih.gov/pubmed/35634269
http://dx.doi.org/10.1021/acssuschemeng.2c01180