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Role of EZH2-mediated H3K27me3 in placental ADAM12-S expression: implications for fetoplacental growth

BACKGROUND: Enhancer of zeste homolog 2 (EZH2)-mediated histone 3 lysine 27 trimethylation (H3K27me3) is a transcription silencing mark, which is indispensable for cell lineage specification at the early blastocyst stage. This epigenetic repression is maintained in placental cytotrophoblasts but is...

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Detalles Bibliográficos
Autores principales: Zhu, Ya-nan, Gan, Xiao-wen, Pan, Fan, Ni, Xiao-tian, Myatt, Leslie, Wang, Wang-sheng, Sun, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131539/
https://www.ncbi.nlm.nih.gov/pubmed/35610640
http://dx.doi.org/10.1186/s12916-022-02391-4