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Role of EZH2-mediated H3K27me3 in placental ADAM12-S expression: implications for fetoplacental growth
BACKGROUND: Enhancer of zeste homolog 2 (EZH2)-mediated histone 3 lysine 27 trimethylation (H3K27me3) is a transcription silencing mark, which is indispensable for cell lineage specification at the early blastocyst stage. This epigenetic repression is maintained in placental cytotrophoblasts but is...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131539/ https://www.ncbi.nlm.nih.gov/pubmed/35610640 http://dx.doi.org/10.1186/s12916-022-02391-4 |