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Pharmacokinetics, adverse effects and effects on thermal nociception following administration of three doses of codeine to horses

BACKGROUND: In humans, codeine is a commonly prescribed analgesic that produces its therapeutic effect largely through metabolism to morphine. In some species, analgesic effects of morphine have also been attributed to the morphine-6-glucuronide (M6G) metabolite. Although an effective analgesic, adm...

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Detalles Bibliográficos
Autores principales: Knych, Heather K., Stucker, Kristen, Gretler, Sophie R., Kass, Philip H., McKemie, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131543/
https://www.ncbi.nlm.nih.gov/pubmed/35614473
http://dx.doi.org/10.1186/s12917-022-03299-0