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Exogenous leptin enhances markers of airway fibrosis in a mouse model of chronic allergic airways disease
BACKGROUND: Asthma patients with comorbid obesity exhibit increased disease severity, in part, due to airway remodeling, which is also observed in mouse models of asthma and obesity. A mediator of remodeling that is increased in obesity is leptin. We hypothesized that in a mouse model of allergic ai...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131622/ https://www.ncbi.nlm.nih.gov/pubmed/35610699 http://dx.doi.org/10.1186/s12931-022-02048-z |