Exogenous leptin enhances markers of airway fibrosis in a mouse model of chronic allergic airways disease

BACKGROUND: Asthma patients with comorbid obesity exhibit increased disease severity, in part, due to airway remodeling, which is also observed in mouse models of asthma and obesity. A mediator of remodeling that is increased in obesity is leptin. We hypothesized that in a mouse model of allergic ai...

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Detalles Bibliográficos
Autores principales: Ihrie, Mark D., McQuade, Victoria L., Womble, Jack T., Hegde, Akhil, McCravy, Matthew S., Lacuesta, Cyrus Victor G., Tighe, Robert M., Que, Loretta G., Walker, Julia K. L., Ingram, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131622/
https://www.ncbi.nlm.nih.gov/pubmed/35610699
http://dx.doi.org/10.1186/s12931-022-02048-z

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