Cholecystectomy promotes colon carcinogenesis by activating the Wnt signaling pathway by increasing the deoxycholic acid level

PURPOSE: Cholecystectomy (XGB) is widely recognized as a risk factor for colon cancer (CC). Continuous exposure of the colonic epithelium to deoxycholic acid (DCA) post-XGB may exert cytotoxic effects and be involved in the progression of CC. However, the functions of the XGB-induced DCA increase an...

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Detalles Bibliográficos
Autores principales: Yao, Yuxia, Li, Xiangji, Xu, Baohong, Luo, Li, Guo, Qingdong, Wang, Xingyu, Sun, Lan, Zhang, Zheng, Li, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131663/
https://www.ncbi.nlm.nih.gov/pubmed/35614513
http://dx.doi.org/10.1186/s12964-022-00890-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131663/
https://www.ncbi.nlm.nih.gov/pubmed/35614513
http://dx.doi.org/10.1186/s12964-022-00890-8

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