Targeting TROY-mediated P85a/AKT/TBX3 signaling attenuates tumor stemness and elevates treatment response in hepatocellular carcinoma

BACKGROUND: Previous in vitro hepatocyte differentiation model showed that TROY was specifically expressed in liver progenitor cells and a small proportion of hepatocellular carcinoma cells, suggesting that TROY may participate in hepatocellular carcinoma (HCC) stemness regulation. Here, we aim to i...

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Detalles Bibliográficos
Autores principales: Liu, Beilei, Fang, Xiaona, Kwong, Dora Lai-Wan, Zhang, Yu, Verhoeft, Krista, Gong, Lanqi, Zhang, Baifeng, Chen, Jie, Yu, Qianqian, Luo, Jie, Tang, Ying, Huang, Tuxiong, Ling, Fei, Fu, Li, Yan, Qian, Guan, Xin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131684/
https://www.ncbi.nlm.nih.gov/pubmed/35610614
http://dx.doi.org/10.1186/s13046-022-02401-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131684/
https://www.ncbi.nlm.nih.gov/pubmed/35610614
http://dx.doi.org/10.1186/s13046-022-02401-6

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