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Metformin exerts an antitumor effect by inhibiting bladder cancer cell migration and growth, and promoting apoptosis through the PI3K/AKT/mTOR pathway

BACKGROUND: To observe and explore the effect of metformin on the migration and proliferation of bladder cancer T24 and 5637 cells in vitro. METHODS: Bladder cancer T24 and 5637 cell lines were cultured in vitro, and were divided into group A (blank control group) and group B (metformin group: 5, 10...

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Detalles Bibliográficos
Autores principales: Shen, Zhiyong, Xue, Dong, Wang, Kun, Zhang, Facai, Shi, Jiaqi, Jia, Benzhong, Yang, Dan, Zhang, Qianjin, Zhang, Shuai, Jiang, Hongyu, Luo, Daiqin, Li, Xueying, Zhong, Quliang, Zhang, Junhao, Peng, Zheng, Han, Yu, Sima, Chongyang, He, Xiaozhou, Hao, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131696/
https://www.ncbi.nlm.nih.gov/pubmed/35610639
http://dx.doi.org/10.1186/s12894-022-01027-2