Cargando…
Metformin exerts an antitumor effect by inhibiting bladder cancer cell migration and growth, and promoting apoptosis through the PI3K/AKT/mTOR pathway
BACKGROUND: To observe and explore the effect of metformin on the migration and proliferation of bladder cancer T24 and 5637 cells in vitro. METHODS: Bladder cancer T24 and 5637 cell lines were cultured in vitro, and were divided into group A (blank control group) and group B (metformin group: 5, 10...
Autores principales: | Shen, Zhiyong, Xue, Dong, Wang, Kun, Zhang, Facai, Shi, Jiaqi, Jia, Benzhong, Yang, Dan, Zhang, Qianjin, Zhang, Shuai, Jiang, Hongyu, Luo, Daiqin, Li, Xueying, Zhong, Quliang, Zhang, Junhao, Peng, Zheng, Han, Yu, Sima, Chongyang, He, Xiaozhou, Hao, Lin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131696/ https://www.ncbi.nlm.nih.gov/pubmed/35610639 http://dx.doi.org/10.1186/s12894-022-01027-2 |
Ejemplares similares
-
Matrine exerts antitumor activity in cervical cancer by protective autophagy via the Akt/mTOR pathway in vitro and in vivo
por: Zhang, Fan, et al.
Publicado: (2022) -
Metformin Attenuates UVA-Induced Skin Photoaging by Suppressing Mitophagy and the PI3K/AKT/mTOR Pathway
por: Chen, Qiuyan, et al.
Publicado: (2022) -
METTL3-mediated m6A modification of KIF3C-mRNA promotes prostate cancer progression and is negatively regulated by miR-320d
por: Ma, Honggui, et al.
Publicado: (2021) -
Shikonin exerts antitumor activity in Burkitt’s lymphoma by inhibiting C-MYC and PI3K/AKT/mTOR pathway and acts synergistically with doxorubicin
por: Ni, Fan, et al.
Publicado: (2018) -
Inhibition of mTOR signaling and clinical activity of metformin in oral premalignant lesions
por: Gutkind, J. Silvio, et al.
Publicado: (2021)