N-Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes

BACKGROUND: The transient receptor potential vanilloid 1 (TRPV1) participates in thermosensation and inflammatory pain, but its immunomodulatory mechanisms remain enigmatic. N-Oleoyl dopamine (OLDA), an endovanilloid and endocannabinoid, is a TRPV1 agonist that is produced in the central nervous sys...

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Detalles Bibliográficos
Autores principales: Joffre, Jérémie, Wong, Erika, Lawton, Samira, Lloyd, Elliot, Nguyen, Nina, Xu, Fengyun, Sempio, Cristina, Kobzik, Lester, Zlatanova, Ivana, Schumacher, Mark, Klawitter, Jost, Su, Hua, Rabl, Katalin, Wilhelmsen, Kevin, Yeh, Che-Chung, Hellman, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131699/
https://www.ncbi.nlm.nih.gov/pubmed/35610647
http://dx.doi.org/10.1186/s12974-022-02485-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131699/
https://www.ncbi.nlm.nih.gov/pubmed/35610647
http://dx.doi.org/10.1186/s12974-022-02485-z

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