Estimating HLA haplotype frequencies from homozygous individuals – A Technical Report

We estimated HLA haplotype frequencies based on individuals homozygous for 4, 5 or 6 loci. Validation of our approach using a sample of over 3.4 million German individuals was successful. Compared to an expectation‐maximization algorithm, the errors were larger. However, our approach allows the uneq...

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Detalles Bibliográficos
Autores principales: Seitz, Susanne, Lange, Vinzenz, Norman, Paul J., Sauter, Jürgen, Schmidt, Alexander H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Population Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131737/
https://www.ncbi.nlm.nih.gov/pubmed/34570965
http://dx.doi.org/10.1111/iji.12553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131737/
https://www.ncbi.nlm.nih.gov/pubmed/34570965
http://dx.doi.org/10.1111/iji.12553

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