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Estimating HLA haplotype frequencies from homozygous individuals – A Technical Report
We estimated HLA haplotype frequencies based on individuals homozygous for 4, 5 or 6 loci. Validation of our approach using a sample of over 3.4 million German individuals was successful. Compared to an expectation‐maximization algorithm, the errors were larger. However, our approach allows the uneq...
Autores principales: | Seitz, Susanne, Lange, Vinzenz, Norman, Paul J., Sauter, Jürgen, Schmidt, Alexander H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131737/ https://www.ncbi.nlm.nih.gov/pubmed/34570965 http://dx.doi.org/10.1111/iji.12553 |
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