Critical roles for EGFR and EGFR–HER2 clusters in EGF binding of SW620 human carcinoma cells

Epidermal growth factor (EGF) signalling regulates normal epithelial and other cell growth, with EGF receptor (EGFR) overexpression reported in many cancers. However, the role of EGFR clusters in cancer and their dependence on EGF binding is unclear. We present novel single-molecule total internal r...

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Detalles Bibliográficos
Autores principales: Wollman, Adam J. M., Fournier, Charlotte, Llorente-Garcia, Isabel, Harriman, Oliver, Payne-Dwyer, Alex L., Shashkova, Sviatlana, Zhou, Peng, Liu, Ta-Chun, Ouaret, Djamila, Wilding, Jenny, Kusumi, Akihiro, Bodmer, Walter, Leake, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Life Sciences–Physics interface
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131850/
https://www.ncbi.nlm.nih.gov/pubmed/35612280
http://dx.doi.org/10.1098/rsif.2022.0088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131850/
https://www.ncbi.nlm.nih.gov/pubmed/35612280
http://dx.doi.org/10.1098/rsif.2022.0088

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