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Critical roles for EGFR and EGFR–HER2 clusters in EGF binding of SW620 human carcinoma cells
Epidermal growth factor (EGF) signalling regulates normal epithelial and other cell growth, with EGF receptor (EGFR) overexpression reported in many cancers. However, the role of EGFR clusters in cancer and their dependence on EGF binding is unclear. We present novel single-molecule total internal r...
Autores principales: | Wollman, Adam J. M., Fournier, Charlotte, Llorente-Garcia, Isabel, Harriman, Oliver, Payne-Dwyer, Alex L., Shashkova, Sviatlana, Zhou, Peng, Liu, Ta-Chun, Ouaret, Djamila, Wilding, Jenny, Kusumi, Akihiro, Bodmer, Walter, Leake, Mark C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131850/ https://www.ncbi.nlm.nih.gov/pubmed/35612280 http://dx.doi.org/10.1098/rsif.2022.0088 |
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