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Four AAs increase DMT1 abundance in duodenal brush-border membrane vesicles and enhance iron absorption in iron-deprived mice

Iron-deficiency anemia is common worldwide and typically treated by oral iron supplementation. Excess enteral iron, however, may cause pathological outcomes. Developing new repletion approaches is thus warranted. Previous experimentation revealed that select amino acids (AAs) induce trafficking of t...

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Detalles Bibliográficos
Autores principales: Woloshun, Regina R., Yu, Yang, Xu, Xiaodong, Lee, Jennifer K., Zhu, Sean, Shine, Jacob S., Ebea, Pearl, Stevens, Bruce R., Vidyasagar, Sadasivan, Collins, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131898/
https://www.ncbi.nlm.nih.gov/pubmed/35061889
http://dx.doi.org/10.1182/bloodadvances.2021005111