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Four AAs increase DMT1 abundance in duodenal brush-border membrane vesicles and enhance iron absorption in iron-deprived mice
Iron-deficiency anemia is common worldwide and typically treated by oral iron supplementation. Excess enteral iron, however, may cause pathological outcomes. Developing new repletion approaches is thus warranted. Previous experimentation revealed that select amino acids (AAs) induce trafficking of t...
Autores principales: | Woloshun, Regina R., Yu, Yang, Xu, Xiaodong, Lee, Jennifer K., Zhu, Sean, Shine, Jacob S., Ebea, Pearl, Stevens, Bruce R., Vidyasagar, Sadasivan, Collins, James F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131898/ https://www.ncbi.nlm.nih.gov/pubmed/35061889 http://dx.doi.org/10.1182/bloodadvances.2021005111 |
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