Cargando…
Anti-HK antibody reveals critical roles of a 20-residue HK region for Aβ-induced plasma contact system activation
Alzheimer’s disease (AD) is a neurodegenerative disorder and the leading cause of dementia. Vascular abnormalities and neuroinflammation play roles in AD pathogenesis. Plasma contact activation, which leads to fibrin clot formation and bradykinin release, is elevated in many AD patients, likely due...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Hematology
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131899/ https://www.ncbi.nlm.nih.gov/pubmed/35147669 http://dx.doi.org/10.1182/bloodadvances.2021006612 |