MicroRNA-31 regulates T-cell metabolism via HIF1α and promotes chronic GVHD pathogenesis in mice

Chronic graft-versus-host disease (cGVHD) remains a major obstacle impeding successful allogeneic hematopoietic cell transplantation (HCT). MicroRNAs (miRs) play key roles in immune regulation during acute GVHD development. Preclinical studies to identify miRs that affect cGVHD pathogenesis are requ...

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Detalles Bibliográficos
Autores principales: Wu, Yongxia, Mealer, Corey, Schutt, Steven, Wilson, Carole L., Bastian, David, Sofi, M. Hanief, Zhang, Mengmeng, Luo, Zhenwu, Choi, Hee-Jin, Yang, Kaipo, Tian, Linlu, Nguyen, Hung, Helke, Kris, Schnapp, Lynn M., Wang, Honglin, Yu, Xue-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131913/
https://www.ncbi.nlm.nih.gov/pubmed/35073581
http://dx.doi.org/10.1182/bloodadvances.2021005103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131913/
https://www.ncbi.nlm.nih.gov/pubmed/35073581
http://dx.doi.org/10.1182/bloodadvances.2021005103

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