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MicroRNA-31 regulates T-cell metabolism via HIF1α and promotes chronic GVHD pathogenesis in mice
Chronic graft-versus-host disease (cGVHD) remains a major obstacle impeding successful allogeneic hematopoietic cell transplantation (HCT). MicroRNAs (miRs) play key roles in immune regulation during acute GVHD development. Preclinical studies to identify miRs that affect cGVHD pathogenesis are requ...
Autores principales: | Wu, Yongxia, Mealer, Corey, Schutt, Steven, Wilson, Carole L., Bastian, David, Sofi, M. Hanief, Zhang, Mengmeng, Luo, Zhenwu, Choi, Hee-Jin, Yang, Kaipo, Tian, Linlu, Nguyen, Hung, Helke, Kris, Schnapp, Lynn M., Wang, Honglin, Yu, Xue-Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131913/ https://www.ncbi.nlm.nih.gov/pubmed/35073581 http://dx.doi.org/10.1182/bloodadvances.2021005103 |
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