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Prognostic value of low-level MRD in adult acute lymphoblastic leukemia detected by low- and high-throughput methods
Persistence of minimal residual disease (MRD) after induction/consolidation therapy in acute lymphoblastic leukemia is the leading cause of relapse. The GMALL 07/2003 study used MRD detection by real-time quantitative polymerase chain reaction of clonal immune gene rearrangements with 1 × 10(−4) as...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131918/ https://www.ncbi.nlm.nih.gov/pubmed/35026836 http://dx.doi.org/10.1182/bloodadvances.2021006727 |