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Prognostic value of low-level MRD in adult acute lymphoblastic leukemia detected by low- and high-throughput methods

Persistence of minimal residual disease (MRD) after induction/consolidation therapy in acute lymphoblastic leukemia is the leading cause of relapse. The GMALL 07/2003 study used MRD detection by real-time quantitative polymerase chain reaction of clonal immune gene rearrangements with 1 × 10(−4) as...

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Detalles Bibliográficos
Autores principales: Kotrová, Michaela, Koopmann, Johannes, Trautmann, Heiko, Alakel, Nael, Beck, Joachim, Nachtkamp, Kathrin, Steffen, Björn, Raffel, Simon, Viardot, Andreas, Wethmar, Klaus, Darzentas, Nikos, Baldus, Claudia D., Gökbuget, Nicola, Brüggemann, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131918/
https://www.ncbi.nlm.nih.gov/pubmed/35026836
http://dx.doi.org/10.1182/bloodadvances.2021006727