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K(+) efflux through postsynaptic NMDA receptors suppresses local astrocytic glutamate uptake
Glutamatergic transmission prompts K(+) efflux through postsynaptic NMDA receptors. The ensuing hotspot of extracellular K(+) elevation depolarizes presynaptic terminal, boosting glutamate release, but whether this also affects glutamate uptake in local astroglia has remained an intriguing question....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132042/ https://www.ncbi.nlm.nih.gov/pubmed/35084774 http://dx.doi.org/10.1002/glia.24150 |