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A bioorthogonal chemical reporter for the detection and identification of protein lactylation

l-Lactylation is a recently discovered post-translational modification occurring on histone lysine residues to regulate gene expression. However, the substrate scope of lactylation, especially that in non-histone proteins, remains unknown, largely due to the limitations of current methods for analyz...

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Detalles Bibliográficos
Autores principales: Sun, Yanan, Chen, Yanchi, Peng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132054/
https://www.ncbi.nlm.nih.gov/pubmed/35685793
http://dx.doi.org/10.1039/d2sc00918h