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The Iron Response of Mycobacterium tuberculosis and Its Implications for Tuberculosis Pathogenesis and Novel Therapeutics

Most pathogenic bacteria require iron for growth. However, this metal is not freely available in the mammalian host. Due to its poor solubility and propensity to catalyze the generation of reactive oxygen species, host iron is kept in solution bound to specialized iron binding proteins. Access to ir...

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Detalles Bibliográficos
Autores principales: Rodriguez, G. Marcela, Sharma, Nishant, Biswas, Ashis, Sharma, Nevadita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132128/
https://www.ncbi.nlm.nih.gov/pubmed/35646739
http://dx.doi.org/10.3389/fcimb.2022.876667