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HOXB9 mediates resistance to chemotherapy and patient outcomes through the TGFβ pathway in pancreatic cancer

Background: Although HOXB9 induces tumor proliferation and chemoresistance in several cancer cells, little is known in pancreatic ductal adenocarcinoma (PDAC). In the present study, increased expression of HOXB9 in PDAC was associated with the induction of angiogenic factors and poor overall surviva...

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Detalles Bibliográficos
Autores principales: Chiba, Naokazu, Ochiai, Shigeto, Gunji, Takahiro, Kobayashi, Toshimichi, Sano, Toru, Tomita, Koichi, Kawachi, Shigeyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132260/
https://www.ncbi.nlm.nih.gov/pubmed/35634239
http://dx.doi.org/10.18632/oncotarget.28235