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Characterization and clustering of kinase isoform expression in metastatic melanoma

Mutations to the human kinome are known to play causal roles in cancer. The kinome regulates numerous cell processes including growth, proliferation, differentiation, and apoptosis. In addition to aberrant expression, aberrant alternative splicing of cancer-driver genes is receiving increased attent...

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Detalles Bibliográficos
Autores principales: Holland, David O., Gotea, Valer, Fedkenheuer, Kevin, Jaiswal, Sushil K., Baugher, Catherine, Tan, Hua, Fedkenheuer, Michael, Elnitski, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132324/
https://www.ncbi.nlm.nih.gov/pubmed/35560144
http://dx.doi.org/10.1371/journal.pcbi.1010065