Cargando…
Characterization and clustering of kinase isoform expression in metastatic melanoma
Mutations to the human kinome are known to play causal roles in cancer. The kinome regulates numerous cell processes including growth, proliferation, differentiation, and apoptosis. In addition to aberrant expression, aberrant alternative splicing of cancer-driver genes is receiving increased attent...
Autores principales: | Holland, David O., Gotea, Valer, Fedkenheuer, Kevin, Jaiswal, Sushil K., Baugher, Catherine, Tan, Hua, Fedkenheuer, Michael, Elnitski, Laura |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132324/ https://www.ncbi.nlm.nih.gov/pubmed/35560144 http://dx.doi.org/10.1371/journal.pcbi.1010065 |
Ejemplares similares
-
Bidirectional Promoters as Important Drivers for the Emergence of Species-Specific Transcripts
por: Gotea, Valer, et al.
Publicado: (2013) -
Tissue-Specific and Ubiquitous Expression Patterns from Alternative Promoters of Human Genes
por: Jacox, Edwin, et al.
Publicado: (2010) -
Pan-cancer stratification of solid human epithelial tumors and cancer cell lines reveals commonalities and tissue-specific features of the CpG island methylator phenotype
por: Sánchez-Vega, Francisco, et al.
Publicado: (2015) -
Significant associations between driver gene mutations and DNA methylation alterations across many cancer types
por: Chen, Yun-Ching, et al.
Publicado: (2017) -
CpG island methylator phenotype in adenocarcinomas from the digestive tract: Methods, conclusions, and controversies
por: Sánchez-Vega, Francisco, et al.
Publicado: (2017)