TH-MYCN tumors, but not tumor-derived cell lines, are adrenergic lineage, GD2+, and responsive to anti-GD2 antibody therapy

Neuroblastoma is a commonly lethal solid tumor of childhood and intensive chemoradiotherapy treatment cures ~50% of children with high-risk disease. The addition of immunotherapy using dinutuximab, a monoclonal antibody directed against the GD2 disialoganglioside expressed on neuroblasts, improves s...

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Detalles Bibliográficos
Autores principales: McNerney, KO, Karageorgos, S, Ferry, GM, Wolpaw, AJ, Burudpakdee, C, Khurana, P, Toland, CN, Vemu, R, Vu, A, Hogarty, MD, Bassiri, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132414/
https://www.ncbi.nlm.nih.gov/pubmed/35646475
http://dx.doi.org/10.1080/2162402X.2022.2075204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132414/
https://www.ncbi.nlm.nih.gov/pubmed/35646475
http://dx.doi.org/10.1080/2162402X.2022.2075204

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