From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge Dendrilla antarctica

Nature has been always a great source of possible lead compounds to develop new drugs against several diseases. Here we report the identification of a natural compound, membranoid G, derived from the Antarctic sponge Dendrilla antarctica displaying an in vitro inhibitory activity against human DNA t...

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Detalles Bibliográficos
Autores principales: Ottaviani, Alessio, Welsch, Joshua, Agama, Keli, Pommier, Yves, Desideri, Alessandro, Baker, Bill J., Fiorani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132426/
https://www.ncbi.nlm.nih.gov/pubmed/35603503
http://dx.doi.org/10.1080/14756366.2022.2078320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132426/
https://www.ncbi.nlm.nih.gov/pubmed/35603503
http://dx.doi.org/10.1080/14756366.2022.2078320

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