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From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge Dendrilla antarctica
Nature has been always a great source of possible lead compounds to develop new drugs against several diseases. Here we report the identification of a natural compound, membranoid G, derived from the Antarctic sponge Dendrilla antarctica displaying an in vitro inhibitory activity against human DNA t...
Autores principales: | Ottaviani, Alessio, Welsch, Joshua, Agama, Keli, Pommier, Yves, Desideri, Alessandro, Baker, Bill J., Fiorani, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132426/ https://www.ncbi.nlm.nih.gov/pubmed/35603503 http://dx.doi.org/10.1080/14756366.2022.2078320 |
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