E-site drug specificity of the human pathogen Candida albicans ribosome

Candida albicans is a widespread commensal fungus with substantial pathogenic potential and steadily increasing resistance to current antifungal drugs. It is known to be resistant to cycloheximide (CHX) that binds to the E–transfer RNA binding site of the ribosome. Because of lack of structural info...

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Detalles Bibliográficos
Autores principales: Zgadzay, Yury, Kolosova, Olga, Stetsenko, Artem, Wu, Cheng, Bruchlen, David, Usachev, Konstantin, Validov, Shamil, Jenner, Lasse, Rogachev, Andrey, Yusupova, Gulnara, Sachs, Matthew S., Guskov, Albert, Yusupov, Marat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132455/
https://www.ncbi.nlm.nih.gov/pubmed/35613268
http://dx.doi.org/10.1126/sciadv.abn1062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132455/
https://www.ncbi.nlm.nih.gov/pubmed/35613268
http://dx.doi.org/10.1126/sciadv.abn1062

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