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E-site drug specificity of the human pathogen Candida albicans ribosome
Candida albicans is a widespread commensal fungus with substantial pathogenic potential and steadily increasing resistance to current antifungal drugs. It is known to be resistant to cycloheximide (CHX) that binds to the E–transfer RNA binding site of the ribosome. Because of lack of structural info...
Autores principales: | Zgadzay, Yury, Kolosova, Olga, Stetsenko, Artem, Wu, Cheng, Bruchlen, David, Usachev, Konstantin, Validov, Shamil, Jenner, Lasse, Rogachev, Andrey, Yusupova, Gulnara, Sachs, Matthew S., Guskov, Albert, Yusupov, Marat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132455/ https://www.ncbi.nlm.nih.gov/pubmed/35613268 http://dx.doi.org/10.1126/sciadv.abn1062 |
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