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Guanylate-Binding protein 2b regulates the AMPK/mTOR/ULK1 signalling pathway to induce autophagy during Mycobacterium bovis infection

Autophagic isolation and degradation of intracellular pathogens are employed by host cells as primary innate immune defense mechanisms to control intercellular M. bovis infection. In this study, RNA-Seq technology was used to obtain the total mRNA from bone marrow-derived macrophages (BMDMs) infecte...

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Detalles Bibliográficos
Autores principales: Yu, Youli, Pan, Jialiang, Liu, Mengting, Jiang, Haiqin, Xiong, Jingshu, Tao, Lei, Xue, Feng, Tang, Fang, Wang, Hongsheng, Dai, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132469/
https://www.ncbi.nlm.nih.gov/pubmed/35531887
http://dx.doi.org/10.1080/21505594.2022.2073024