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FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression

Pancreatic cancer (PC) is one of the deadliest malignant tumors, and its resistance to gemcitabine chemotherapy is the primary reason for poor prognosis in patients. Ubiquitin-like protein FAT10 has recently been reported to promote tumor chemotherapy resistance. In this study, the expression of FAT...

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Detalles Bibliográficos
Autores principales: Zhu, Jinfeng, Zhao, Jiefeng, Luo, Chen, Zhu, Zhengming, Peng, Xingyu, Zhu, Xiaojian, Lin, Kang, Bu, Fanqin, Zhang, Wenjun, Li, Qing, Wang, Kai, Hu, Zhigang, Yu, Xin, Chen, Leifeng, Yuan, Rongfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132907/
https://www.ncbi.nlm.nih.gov/pubmed/35614040
http://dx.doi.org/10.1038/s41419-022-04960-0