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FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression
Pancreatic cancer (PC) is one of the deadliest malignant tumors, and its resistance to gemcitabine chemotherapy is the primary reason for poor prognosis in patients. Ubiquitin-like protein FAT10 has recently been reported to promote tumor chemotherapy resistance. In this study, the expression of FAT...
Autores principales: | Zhu, Jinfeng, Zhao, Jiefeng, Luo, Chen, Zhu, Zhengming, Peng, Xingyu, Zhu, Xiaojian, Lin, Kang, Bu, Fanqin, Zhang, Wenjun, Li, Qing, Wang, Kai, Hu, Zhigang, Yu, Xin, Chen, Leifeng, Yuan, Rongfa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132907/ https://www.ncbi.nlm.nih.gov/pubmed/35614040 http://dx.doi.org/10.1038/s41419-022-04960-0 |
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