Cargando…

Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain

Proteomic profiling of brain cell types using isolation-based strategies pose limitations in resolving cellular phenotypes representative of their native state. We describe a mouse line for cell type-specific expression of biotin ligase TurboID, for in vivo biotinylation of proteins. Using adenovira...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rayaprolu, Sruti, Bitarafan, Sara, Santiago, Juliet V., Betarbet, Ranjita, Sunna, Sydney, Cheng, Lihong, Xiao, Hailian, Nelson, Ruth S., Kumar, Prateek, Bagchi, Pritha, Duong, Duc M., Goettemoeller, Annie M., Oláh, Viktor János, Rowan, Matt, Levey, Allan I., Wood, Levi B., Seyfried, Nicholas T., Rangaraju, Srikant
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132937/ https://www.ncbi.nlm.nih.gov/pubmed/35614064 http://dx.doi.org/10.1038/s41467-022-30623-x

Ejemplares similares

Cellular Proteomic Profiling Using Proximity Labeling by TurboID-NES in Microglial and Neuronal Cell Lines
por: Sunna, Sydney, et al.
Publicado: (2023)

Systems-based proteomics to resolve the biology of Alzheimer’s disease beyond amyloid and tau
por: Rayaprolu, Sruti, et al.
Publicado: (2020)

Biophysical K(v)3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer’s
por: Olah, Viktor J, et al.
Publicado: (2022)

Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer’s disease
por: Rayaprolu, Sruti, et al.
Publicado: (2020)

Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles
por: Santiago, Juliet V., et al.
Publicado: (2023)

Differential Phagocytic Properties of CD45(low) Microglia and CD45(high) Brain Mononuclear Phagocytes—Activation and Age-Related Effects
por: Rangaraju, Srikant, et al.
Publicado: (2018)

Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer’s disease-related proteins
por: Rangaraju, Srikant, et al.
Publicado: (2018)

Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology
por: Goettemoeller, Annie M, et al.
Publicado: (2023)

A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation
por: Rangaraju, Srikant, et al.
Publicado: (2017)

Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease
por: Rangaraju, Srikant, et al.
Publicado: (2018)

Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms
por: Nelson, Ruth S., et al.
Publicado: (2022)

Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome
por: Zlatic, Stephanie A., et al.
Publicado: (2022)

Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer’s disease
por: Wang, Erming, et al.
Publicado: (2023)

Temporal profiling of Kv1.3 channel expression in brain mononuclear phagocytes following ischemic stroke
por: Gao, Tianwen, et al.
Publicado: (2019)

Pesticides and Parkinson’s Disease
por: Sherer, Todd B., et al.
Publicado: (2001)

APOE expression and secretion are modulated by mitochondrial dysfunction
por: Wynne, Meghan E, et al.
Publicado: (2023)

BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia
por: Sudwarts, Ari, et al.
Publicado: (2022)

Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells
por: Sarkar, Souvarish, et al.
Publicado: (2020)

Overexpression of biotin synthase and biotin ligase is required for efficient generation of sulfur-35 labeled biotin in E. coli
por: Delli-Bovi, Teegan A, et al.
Publicado: (2010)

Extracellular calcium alters calcium-sensing receptor network integrating intracellular calcium-signaling and related key pathway
por: Gorkhali, Rakshya, et al.
Publicado: (2021)

A biotin-streptavidin-biotin bridge dramatically enhances cell fusion
por: LI, JINHUA, et al.
Publicado: (2014)

Biotin Auxotrophy and Biotin Enhanced Germ Tube Formation in Candida albicans
por: Ahmad Hussin, Nur, et al.
Publicado: (2016)

Development and Evaluation of an Anti-Biotin Interference Method in Biotin-Streptavidin Immunoassays
por: Liu, Dong, et al.
Publicado: (2022)

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism
por: Belda, Eugeni, et al.
Publicado: (2022)

A versatile Escherichia coli strain for identification of biotin transporters and for biotin quantification
por: Finkenwirth, Friedrich, et al.
Publicado: (2014)

Chemistry of Biotin–Streptavidin and the Growing Concern of an Emerging Biotin Interference in Clinical Immunoassays
por: Luong, John H. T., et al.
Publicado: (2019)

Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling
por: Pranski, Elaine L, et al.
Publicado: (2012)

Comment on “High doses of biotin can interfere with immunoassays that use biotin-strept(avidin) technologies: Implications for individuals with biotin-responsive inherited metabolic disorders”
por: Favresse, Julien, et al.
Publicado: (2019)

Thermophoresis: The Case of Streptavidin and Biotin
por: Niether, Doreen, et al.
Publicado: (2020)

Characterization of the biotin uptake system encoded by the biotin-inducible bioYMN operon of Corynebacterium glutamicum
por: Schneider, Jens, et al.
Publicado: (2012)

The overlooked role of a biotin precursor for marine bacteria - desthiobiotin as an escape route for biotin auxotrophy
por: Wienhausen, Gerrit, et al.
Publicado: (2022)

Response to comment on “High doses of biotin can interfere with immunoassays that use biotin-strept(avidin) technologies: Implications for individuals with biotin-responsive inherited metabolic disorders”
por: Wolf, Barry
Publicado: (2019)

THE RELATION TO THE COURSE OF AVIAN MALARIA OF BIOTIN AND A FAT-SOLUBLE MATERIAL HAVING THE BIOLOGICAL ACTIVITIES OF BIOTIN
por: Trager, William
Publicado: (1947)

Abbreviation of the Follow-Up NIH Stroke Scale Using Factor Analysis
por: Raza, Syed Ali, et al.
Publicado: (2017)

THE INFLUENCE OF BIOTIN UPON SUSCEPTIBILITY TO MALARIA
por: Trager, William
Publicado: (1943)

Biotin selective polymer nano-films
por: Elmlund, Louise, et al.
Publicado: (2014)

Biotin Is Required for the Zinc Homeostasis in the Skin
por: Ogawa, Youichi, et al.
Publicado: (2019)

A sandwich-type electrochemical immunosensor based on the biotin- streptavidin-biotin structure for detection of human immunoglobulin G
por: Li, Yueyun, et al.
Publicado: (2016)

The Atypical Occurrence of Two Biotin Protein Ligases in Francisella novicida Is Due to Distinct Roles in Virulence and Biotin Metabolism
por: Feng, Youjun, et al.
Publicado: (2015)

Reduction of oocyte lipid droplets and meiotic failure due to biotin deficiency was not rescued by restoring the biotin nutritional status
por: Tsuji, Ai, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q3e3a781pvrup0v5jv8598j38a