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SOX17-mediated MALAT1-miR-199a-HIF1α axis confers sensitivity in esophageal squamous cell carcinoma cells to radiotherapy

Radiotherapy is a main modality of esophageal squamous cell carcinoma (ESCC) treatment, while radioresistance largely limits the effect of this therapy. Evidence exists reporting that SOX17 may sensitize ESCC cells to irradiation, but the downstream mechanism remains poorly understood. Therefore, we...

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Detalles Bibliográficos
Autores principales: Yun, Yifei, Zhang, Yutong, Xu, Qiqi, Ou, Yao, Zhou, Xifa, Lu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132944/
https://www.ncbi.nlm.nih.gov/pubmed/35614065
http://dx.doi.org/10.1038/s41420-022-01012-6