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The effect of apigenin and chemotherapy combination treatments on apoptosis-related genes and proteins in acute leukaemia cell lines

Apigenin is a dietary polyphenol found abundantly in fruit and vegetables, which sensitizes leukaemia cells to topoisomerase inhibitor agents (e.g., etoposide), and alkylating agents (e.g., cyclophosphamide), reducing ATP levels and inducing apoptosis; whilst being protective to control haematopoiet...

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Detalles Bibliográficos
Autores principales: Mahbub, Amani A., Le Maitre, Christine L., Cross, Neil A., Jordan-Mahy, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132959/
https://www.ncbi.nlm.nih.gov/pubmed/35614109
http://dx.doi.org/10.1038/s41598-022-11441-z