Chronic treatment with serelaxin mitigates adverse remodeling in a murine model of ischemic heart failure and modulates bioactive sphingolipid signaling

Relaxin is a pleiotropic hormone demonstrated to confer cardioprotection in animal models of myocardial infarction and ischemic heart failure by modulating inflammation, fibrosis and arrhythmogenesis. Several of these pathways in the ischemic myocardium are intricately tied with the downstream signa...

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Detalles Bibliográficos
Autores principales: Devarakonda, Teja, Valle Raleigh, Juan, Mauro, Adolfo G., Lambert, Johana M., Cowart, Lauren Ashley, Salloum, Fadi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132995/
https://www.ncbi.nlm.nih.gov/pubmed/35614179
http://dx.doi.org/10.1038/s41598-022-12930-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132995/
https://www.ncbi.nlm.nih.gov/pubmed/35614179
http://dx.doi.org/10.1038/s41598-022-12930-x

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