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Dysfunction of the energy sensor NFE2L1 triggers uncontrollable AMPK signaling and glucose metabolism reprogramming

The antioxidant transcription factor NFE2L1 (also called Nrf1) acts as a core regulator of redox signaling and metabolism homeostasis, and thus, its dysfunction results in multiple systemic metabolic diseases. However, the molecular mechanism(s) by which NFE2L1 regulates glycose and lipid metabolism...

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Detalles Bibliográficos
Autores principales:	Qiu, Lu, Yang, Qiufang, Zhao, Wenshan, Xing, Yadi, Li, Peng, Zhou, Xiaowen, Ning, Haoming, Shi, Ranran, Gou, Shanshan, Chen, Yalan, Zhai, Wenjie, Wu, Yahong, Li, Guodong, Chen, Zhenzhen, Ren, Yonggang, Gao, Yanfeng, Zhang, Yiguo, Qi, Yuanming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133051/ https://www.ncbi.nlm.nih.gov/pubmed/35614059 http://dx.doi.org/10.1038/s41419-022-04917-3

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