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COUNTERACTING EPIGENETIC MECHANISMS REGULATE THE STRUCTURAL DEVELOPMENT OF NEURONAL CIRCUITRY IN HUMAN NEURONS

Autism spectrum disorders (ASD) are associated with defects in neuronal connectivity and are highly heritable. Genetic findings suggest that there is an overrepresentation of chromatin regulatory genes among the genes associated with ASD. ASH1 like histone lysine methyltransferase (ASH1L) was identi...

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Detalles Bibliográficos
Autores principales: Cheon, Seonhye, Culver, Allison M., Bagnell, Anna M., Ritchie, Foster D., Vacharasin, Janay M., McCord, Mykayla M., Papendorp, Carin M., Chukwurah, Evelyn, Smith, Austin J., Cowen, Mara H., Moreland, Trevor A., Ghate, Pankaj S., Davis, Shannon W., Liu, Judy S., Lizarraga, Sofia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133078/
https://www.ncbi.nlm.nih.gov/pubmed/35210569
http://dx.doi.org/10.1038/s41380-022-01474-1