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A high-throughput multiparameter screen for accelerated development and optimization of soluble genetically encoded fluorescent biosensors

Genetically encoded fluorescent biosensors are powerful tools used to track chemical processes in intact biological systems. However, the development and optimization of biosensors remains a challenging and labor-intensive process, primarily due to technical limitations of methods for screening cand...

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Detalles Bibliográficos
Autores principales: Koveal, Dorothy, Rosen, Paul C., Meyer, Dylan J., Díaz-García, Carlos Manlio, Wang, Yongcheng, Cai, Li-Heng, Chou, Peter J., Weitz, David A., Yellen, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133083/
https://www.ncbi.nlm.nih.gov/pubmed/35614105
http://dx.doi.org/10.1038/s41467-022-30685-x