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TP53 common variants and interaction with PPP1R13L and CD3EAP SNPs and lung cancer risk and smoking behavior in a Chinese population

BACKGROUND: TP53 encodes a tumor suppressor protein containing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. The effect of TP53 inactivation is well-known, and genetically determined smaller variations in TP53 activity are related to cancer. Lung cancer causes the h...

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Detalles Bibliográficos
Autores principales: Yin, Jiaoyang, Hou, Wei, Vogel, Ulla, Li, Xinxin, Ma, Yegang, Wang, Chunhong, Wang, Huiwen, Sun, Zhenxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133261/
https://www.ncbi.nlm.nih.gov/pubmed/35351459
http://dx.doi.org/10.1016/j.bj.2021.01.006