An Imidazoline 2 Receptor Ligand Relaxes Mouse Aorta via Off-Target Mechanisms Resistant to Aging

Imidazoline receptors (IR) are classified into three receptor subtypes (I(1)R, I(2)R, and I(3)R) and previous studies showed that regulation of I(2)R signaling has neuroprotective potential. In order to know if I(2)R has a role in modulating vascular tone in health and disease, we evaluated the puta...

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Detalles Bibliográficos
Autores principales: Jiménez-Altayó, Francesc, Cabrera, Anna, Bagán, Andrea, Giménez-Llort, Lydia, D’Ocon, Pilar, Pérez, Belén, Pallàs, Mercè, Escolano, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133327/
https://www.ncbi.nlm.nih.gov/pubmed/35645795
http://dx.doi.org/10.3389/fphar.2022.826837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133327/
https://www.ncbi.nlm.nih.gov/pubmed/35645795
http://dx.doi.org/10.3389/fphar.2022.826837

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