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Arsenic Trioxide Therapy During Pregnancy: ATO and Its Metabolites in Maternal Blood and Amniotic Fluid of Acute Promyelocytic Leukemia Patients

Acute promyelocytic leukemia (APL) is extremely fatal if treatment is delayed. Management of APL in pregnancy is a challenging situation. Arsenic trioxide (ATO) is successfully applied to treat APL. ATO can be transformed into different arsenic species [arsenite (As(III)), monomethylated arsenic (MM...

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Detalles Bibliográficos
Autores principales: Guo, Meihua, Lv, Jian, Chen, Xiaotong, Wu, Mengliang, Zhao, Qilei, Hai, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133345/
https://www.ncbi.nlm.nih.gov/pubmed/35646703
http://dx.doi.org/10.3389/fonc.2022.887026