Cell-Based HIF1α Gene Therapy Reduces Myocardial Scar and Enhances Angiopoietic Proteome, Transcriptomic and miRNA Expression in Experimental Chronic Left Ventricular Dysfunction

Recent preclinical investigations and clinical trials with stem cells mostly studied bone-marrow-derived mononuclear cells (BM-MNCs), which so far failed to meet clinically significant functional study endpoints. BM-MNCs containing small proportions of stem cells provide little regenerative potentia...

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Detalles Bibliográficos
Autores principales: Gara, Edit, Ong, Sang-Ging, Winkler, Johannes, Zlabinger, Katrin, Lukovic, Dominika, Merkely, Bela, Emmert, Maximilian Y., Wolint, Petra, Hoerstrup, Simon P., Gyöngyösi, Mariann, Wu, Joseph C., Pavo, Noemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133350/
https://www.ncbi.nlm.nih.gov/pubmed/35646882
http://dx.doi.org/10.3389/fbioe.2022.767985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133350/
https://www.ncbi.nlm.nih.gov/pubmed/35646882
http://dx.doi.org/10.3389/fbioe.2022.767985

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