MCC950, a Selective NLRP3 Inhibitor, Attenuates Adverse Cardiac Remodeling Following Heart Failure Through Improving the Cardiometabolic Dysfunction in Obese Mice

Obesity is often accompanied by hypertension. Although a large number of studies have confirmed that NLRP3 inhibitors can improve cardiac remodeling in mice with a normal diet, it is still unclear whether NLRP3 inhibitors can improve heart failure (HF) induced by pressure overload in obese mice. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Menglong, Zhao, Mengmeng, Yu, Junping, Xu, Yao, Zhang, Jishou, Liu, Jianfang, Zheng, Zihui, Ye, Jing, Wang, Zhen, Ye, Di, Feng, Yongqi, Xu, Shuwan, Pan, Wei, Wei, Cheng, Wan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133382/
https://www.ncbi.nlm.nih.gov/pubmed/35647084
http://dx.doi.org/10.3389/fcvm.2022.727474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133382/
https://www.ncbi.nlm.nih.gov/pubmed/35647084
http://dx.doi.org/10.3389/fcvm.2022.727474

Ejemplares similares