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Adeno-associated-virus-mediated gene delivery to ovaries restores fertility in congenital infertile mice

Oocytes and granulosa cells closely interact with each other during follicular development, and a lack of appropriate signaling between them results in infertility. Attempts to manipulate oocyte microenvironment have been impeded by the impermeability of the blood-follicle barrier (BFB). To establis...

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Detalles Bibliográficos
Autores principales: Kanatsu-Shinohara, Mito, Lee, Jiyoung, Miyazaki, Takehiro, Morimoto, Hiroko, Shinohara, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133397/
https://www.ncbi.nlm.nih.gov/pubmed/35584625
http://dx.doi.org/10.1016/j.xcrm.2022.100606