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Adeno-associated-virus-mediated gene delivery to ovaries restores fertility in congenital infertile mice
Oocytes and granulosa cells closely interact with each other during follicular development, and a lack of appropriate signaling between them results in infertility. Attempts to manipulate oocyte microenvironment have been impeded by the impermeability of the blood-follicle barrier (BFB). To establis...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133397/ https://www.ncbi.nlm.nih.gov/pubmed/35584625 http://dx.doi.org/10.1016/j.xcrm.2022.100606 |