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Patient-derived models of brain metastases recapitulate human disseminated disease

Dissemination of cancer cells from primary tumors to the brain occurs in many cancer patients, increasing morbidity and death. There is an unmet medical need to develop translational platforms to evaluate therapeutic responses. Toward this goal, we established a library of 23 patient-derived xenogra...

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Detalles Bibliográficos
Autores principales: Faria, Claudia C., Cascão, Rita, Custódia, Carlos, Paisana, Eunice, Carvalho, Tânia, Pereira, Pedro, Roque, Rafael, Pimentel, José, Miguéns, José, Cortes-Ciriano, Isidro, Barata, João T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133464/
https://www.ncbi.nlm.nih.gov/pubmed/35584628
http://dx.doi.org/10.1016/j.xcrm.2022.100623